Ray Peat on the Benefits of Carbon Dioxide on Cancer Metabolism Interview
In a recent interview by the Herb Doctors on KMUD Friday July 15th 2016 Ray Andrew Murray asked Ray Peat on his views on carbon dioxide in cancer metabolism. Ray mentions 3 ways in which carbon dioxide is beneficial when a cancer metabolism is present. The section of the interview can be seen below. It is 5 minutes and 15 seconds.
Here are the transcripts from this section of the call.
Andrew Murray: You mentioned the inability to relax the over-excitation or the excitotoxic toxic effect of various mediators that promote cancer, and how the cancer itself is in a very excited state, and this constant excitation and the presence of oxygen calms that excitation down.
This is the part that’s unscripted, I wanted to ask you to understand this myself because I know you’re an advocate of CO2 and increasing your CO2 as a definite health benefit. And I know we’ve talked about oxygen being a poison essentially, and I think that’s not a bad word for it.
How is oxygen in this way being a help as opposed to our general understanding of oxygen being a fairly toxic gas?
Ray Peat: The CO2 does at least three central things really to the cancer.
One, it’s acting like a common agent the way ATP does to relax muscles that aren’t stimulated, holding them in a state of readiness to contract.
The CO2 is an analogue of these pigment molecules that Koch and Moses Gomberg were visualizing.
Andrew Murray: So, you said CO2 has a structural similarity to… Because we haven’t even talked about the anthocyanins and flavonoids yet. Is that what you’re saying?
Ray Peat: Yes. It’s acid, a Lewis acid, which doesn’t involve any protons. But the double bonded oxygens on the carbon are the essential feature of the free radical oxidative catalysts that Koch was talking about, and that Albert Szent-Györgyi worked with for about 40 or 50 years. This acidic effect modifies the proteins, so that they are stabilized, calmed down, kept quiet, so that they aren’t forced to shift over to the lactic acid metabolism.
The CO2 also can fill in and correct what’s missing in the Krebs Cycle or the tricarboxylic acid cycle. It’s replenishing the catalytic effect of the fuel that keeps the oxygen process going.
CO2 also directly intervenes in the inhibition of the lactic acid production. So, just by increasing the CO2, breathing in a bag for example for a minute or so at a time several times a day will lower your serum lactic acid.
It’s only in the last two or three years that several people are recognizing that you can diagnose cancer just by an increased chronic lactic acid excess in the blood since it’s one of the factors that keeps the process going, anything that you can do that will shift towards oxidative metabolism and lower your production of lactic acid is helpful.
Sarah Murray: That’s why you recommend for people who have cancer that they go to high elevation, so that they can increase the amount of CO2 in their bloodstream?
Ray Peat: Yeah, there were studies in Russia in the 1960’s in which they gave carcinogens to rats and then they treated some with chemotherapy, and took them to I think it was 17,000 feet altitude and once at high altitude recovered at a very high rate with or without the chemotherapy. The chemotherapy cured a few of them at normal altitude but cured most of them at the high altitude.
About a hundred years ago, the insurance company industry was already aware that the cancer mortality was about 10 percent lower in cities at high altitudes. It was well recognized.
Andrew Murray: Well recognized, because if anyone doesn’t want to lose money, it’s the insurance company.
Thanks so much for explaining that. Let me just remind people again, it’s a live show and callers welcome to call in. I know Dr. Peat enjoys answering questions, the more outside the box the better for him. I really appreciate your explanation of the CO2 at three different mechanisms.
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